Each Magnofenac tablet contains
diclofenac sodium (U.S.P) 50 mg in enteric coated form.
Each Magnofenac Injection contains 75 mg of diclofenac sodium as the active
ingredient in a 3 ml amber-coloured glass ampoule
Description:
Magnofenac belongs to a family
of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It
exerts its anti-inflammatory, analgesic and anti-pyretic effects by
inhibiting the activity of prostaglandin synthetase and lysosomal enzyme.
It relieves pain and inflammation by inhibiting the activity of
prostaglandin
Indications:
Tablet:
Rheumatoid arthritis
Osteoarthritis
Gout
Pain due to trauma
Renal and biliary colic
Injection:
Intramuscular Injection:
Renal colic and biliary
colic
Post-traumatic pain
Osteoarthritis
Rheumatoid arthritis
Ankylosing spondylitis
Severe migraine attacks
Painful syndromes of the
vertebral column
Spondylarthritis
Non-articular rheumatism
Acute attacks of gout
Intravenous Infusion:
Treatment or prevention of
postoperative pain
Dosage:
Tablet:
One tablet 3 times daily
Injection:
Children:
The usage of Magnofenac in children is not recommended.
Adults:
Magnofenac (ampoule) should not be given for more than 2 days.
Intramuscular injection:
Magnofenac (75 mg) given by deep intragluteal injection once or twice
(separated by few hours interval – one into each buttock) daily for maximum
2 days.
Intravenous infusion:
Magnofenac (75 mg) diluted with 0.9% saline or glucose 5% infusion solution
buffered with sodium bicarbonate (100-500 ml) should be infused over a
period of 30 minutes to 2 hours. The therapy should be repeated (after few
hours) according to requirement but maximum dose of 150 mg can be given in
24 hours. For prevention of postoperative pain, loading dose of 25-50 mg
can be infused after surgery in 15-60 minutes, followed by a continuous
infusion of about 5 mg/hour up to maximum dosage of 150 mg daily.
