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PRODUCT
Gluconormet
 
Generic:
Glimepiride
 
Therapeutic Class:
Antidiabetic
 
Composition:

Each Gluconormet (1 mg/ 500 mg) contains glimepiride 1 mg and metformin hydrochloride 500 mg.

Each Gluconormet (2 mg/ 500 mg) contains glimepiride 2 mg and metformin hydrochloride 500 mg.
 
Description:

Gluconormet is an oral antidiabetic agent (glimepiride & metformin HCl) used in the management of type 2 diabetes.

Glimepiride:
Glimepiride (sulphonylurea class), mechanism of action appears to be dependent on stimulating the release of insulin from functioning pancreatic beta cells.


Metformin HCl:
Metformin improves glucose tolerance in patients with type 2 diabetes, lowering both basal and postprandial plasma glucose.

 
Indications:

Gluconormet is indicated in the treatment of patients with type 2 diabetes mellitus when diet, exercise and single agent do not result in adequate glycemic control.

 
Dosage:

Gluconormet should be given once daily with full meal preferably in the evening. Therapy should be started with Gluconormet (glimepiride 1 mg & metformin 500 mg)   one tablet daily. Depending upon the glycemic control, dose may be titrated to 2 tablets once daily.
Alternatively, the therapy may be started with Gluconormet (glimepiride 2 mg & metformin hydrochloride 500 mg) one tablet daily. Depending upon the glycemic control, dose may be titrated to 2 tablets once daily. The maximum daily dose of glimepiride is 8 mg and of metformin is 2000 mg.

 
Presentations:

Gluconormet (1 mg/500 mg) tablet is available in pack of 30’s.
Gluconormet (2 mg/500 mg) tablet is available in pack of 30’s.