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CORE BRANDS
 
PRODUCT
Magnofenac
 
Generic:
Diclofenac Sodium
 
Therapeutic Class:
NSAIDs
 
Composition:
Each Magnofenac tablet contains diclofenac sodium (U.S.P) 50 mg in enteric coated form.

Each Magnofenac Injection contains 75 mg of diclofenac sodium as the active ingredient in a 3 ml amber-coloured glass ampoule
 
Description:
Magnofenac belongs to a family of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It exerts its anti-inflammatory, analgesic and anti-pyretic effects by inhibiting the activity of prostaglandin synthetase and lysosomal enzyme. It relieves pain and inflammation by inhibiting the activity of prostaglandin
 
Indications:
Tablet:
  • Rheumatoid arthritis
  • Osteoarthritis
  • Gout
  • Pain due to trauma
  • Renal and biliary colic


Injection:

Intramuscular Injection:
  • Renal colic and biliary colic
  • Post-traumatic pain
  • Osteoarthritis
  • Rheumatoid arthritis
  • Ankylosing spondylitis
  • Severe migraine attacks
  • Painful syndromes of the vertebral column
  • Spondylarthritis
  • Non-articular rheumatism
  • Acute attacks of gout


Intravenous Infusion:
  • Treatment or prevention of postoperative pain
 
Dosage:
Tablet:
One tablet 3 times daily

Injection:

Children:
The usage of Magnofenac in children is not recommended.

Adults:
Magnofenac (ampoule) should not be given for more than 2 days.

Intramuscular injection:
Magnofenac (75 mg) given by deep intragluteal injection once or twice (separated by few hours interval - one into each buttock) daily for maximum 2 days.

Intravenous infusion:
Magnofenac (75 mg) diluted with 0.9% saline or glucose 5% infusion solution buffered with sodium bicarbonate (100-500 ml) should be infused over a period of 30 minutes to 2 hours. The therapy should be repeated (after few hours) according to requirement but maximum dose of 150 mg can be given in 24 hours. For prevention of postoperative pain, loading dose of 25-50 mg can be infused after surgery in 15-60 minutes, followed by a continuous infusion of about 5 mg/hour up to maximum dosage of 150 mg daily.
 
Presentations:
50 mg tabs 20’s
50 mg tabs 100’s
75 mg Inj. 5’s
75 mg Inj. 50’s