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Calfina INJ


Tramadol HCl


Therapeutic Class:


Non-Narcotic Analgesics




2 ml solution of Calfina
injection contains 100 mg of tramadol hydrochloride.




Calfina Injection contains Tramadol hydrochloride. Tramadol is a centrally acting synthetic opioid analgesic. The analgesic profile of tramadol is attributed to the binding of parent and M1 metabolite to μ-opioid receptors and weak inhibition of reuptake of norepinephrine and serotonin.




Calfina Injection is indicated
for moderate to severe pain. Calfina injection is a potent medicinal
product for the relief of pain, e.g. in wound pain, fractures, severe nerve
pain, tumour pain, heart attack. It should not be used for minor pain.
The-effect sets in quickly and lasts for some hours.




The dose should be adjusted to
the intensity of the pain and the sensitivity of the individual patient.
The lowest effective dose for analgesia should generally be selected. The
total daily dose of 400 mg tramadol hydrochloride should not be exceeded,
except in special clinical circumstances.

The Calfina solution is for parenteral injection either intramuscularly, by slow intravenous injection or diluted in solution for administration by infusion or patient controlled analgesia.


Adults and children 12 years and over:
The usual dose of Calfina is 50 mg or 100 mg 4 to 6 hourly by either intramuscular or intravenous routes. Intravenous injections must be given slowly over 2–3 minutes. The dose should be adjusted according to the severity of the pain and the response.

For post-operative pain, an initial bolus of 100 mg is administered. During the 60 minutes following the initial bolus, further doses of 50 mg may be given every 10-20 minutes, up to a total dose of 250 mg including the initial bolus. Subsequent doses should be 50 mg or 100 mg 4-6 hourly up to a total daily dose of 400 mg.




Calfina® Injection 100 mg – Pack of 5 x 2 ml Ampoules