The dose should be adjusted to
the intensity of the pain and the sensitivity of the individual patient.
The lowest effective dose for analgesia should generally be selected. The
total daily dose of 400 mg tramadol hydrochloride should not be exceeded,
except in special clinical circumstances.
The Calfina solution is for parenteral injection either intramuscularly, by slow intravenous injection or diluted in solution for administration by infusion or patient controlled analgesia.
Adults and children 12 years and over:
The usual dose of Calfina is 50 mg or 100 mg 4 to 6 hourly by either intramuscular or intravenous routes. Intravenous injections must be given slowly over 2–3 minutes. The dose should be adjusted according to the severity of the pain and the response.
For post-operative pain, an initial bolus of 100 mg is administered. During the 60 minutes following the initial bolus, further doses of 50 mg may be given every 10-20 minutes, up to a total dose of 250 mg including the initial bolus. Subsequent doses should be 50 mg or 100 mg 4-6 hourly up to a total daily dose of 400 mg.
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