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Calfina Plus


Acetaminophen, Tramadol HCI


Therapeutic Class:


Non-Narcotic Analgesics




Calfina Plus (Tramadol
hydrochloride/Acetaminophen) tablets contains tramadol 37.5 mg and
acetaminophen 325 mg.




Calfina Plus contains Tramadol hydrochloride & Acetaminophen. Tramadol is a centrally acting synthetic opioid analgesic. The analgesic profile of tramadol is attributed to the binding of parent and M1 metabolite to μ-opioid receptors and weak inhibition of reuptake of norepinephrine and serotonin.
Acetaminophen is a non-opiate, non-salicylate analgesic. Acetaminophen also
has centrally acting analgesic effects.




Calfina Plus is indicated for
management of:

  • Postoperative pain 
  • Musculoskeletal pain 
  • Backache
  • Cirrhotic pain 
  • Pain of acute pharyngitis, acute tonsillitis, acute otitis media 
  • Migraine
  • Painful diabetic peripheral neuropathy
  • Osteoarthritis 
  • Rheumatoid arthritis



Calfina Plus can be used in
adults and children over 16 years of age for the management of acute pain,
the recommended dose of Calfina Plus is 2 tablets every 4 to 6 hours as
needed for pain relief, up to a maximum of 8 tablets per day.




Calfina Plus Tab 10’s