Adults:
Rubiject injection 5-10 ml (100-200 mg iron) 1-3 times / week depending on
the haemoglobin level.
Rubiject injection should be administered intravenously by slow injection
or infusion.
Children:
Under study conditions, there is limited data available. If there is
clinical requirement, Rubiject is recommended not to exceed 0.15 ml (3 mg
iron)/kg body weight 1-3 times/week depending on the haemoglobin level
also.
Recommended Adult Dosage(Chronic kidney disease patients):
Hemodialysis Dependent:
Undiluted Rubiject can be administered as 100 mg slow IV injection in 2-5
minutes or as an infusion of 100 mg, diluted in a maximum of 100 ml of 0.9%
NaCl in atleast 15 minutes per consecutive hemodialysis session for a total
dose of 1000 mg.
Non-Dialysis Dependent:
Rubiject is administered as a total dose of 1000 mg in 14 days as 200 mg
slow IV injection undiluted in 2-5 minutes on 5 different occasions within
14 days.
Peritoneal Dialysis Dependent: Rubiject administered as a total dose of 1000 mg in 3 divided doses, given by slow IV infusion, within 28 days: 2 infusions of 300 mg in 1½ hours 14 days apart followed by one 400 mg infusion in 2½ hours 14 days later. The Rubiject dose should be diluted in a maximum of 250 ml of 0.9% NaCl. .
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