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Home > Products > Rubiject Injection

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Rubiject Injection

Generic:

Iron sucrose

 

Therapeutic Class:

Iron Plain

 

Composition:

Each 5 ml of Rubiject ampoule
contains:
Iron sucrose equivalent to elemental iron … 100 mg

 

Description:

Rubiject (iron sucrose
injection) is an aqueous complex of polynuclear iron (III)-hydroxide in
sucrose for intravenous use.

 

Indications:

Rubiject is recommended in:

  • Conditions in which there
    is clinical requirement for rapid iron supply
  • Active inflammatory bowel
    disease where oral iron preparations are ineffective
  • Iron deficiency due to
    other reasons like final stages of pregnancy, non-responsiveness or
    non-compliance to oral iron therapy, malabsorption, before and after
    surgery etc.

Rubiject is also indicated in
the treatment of iron deficiency anaemia in chronic kidney disease patients
who are:

  • Non-dialysis dependent
    patients receiving or not receiving an erythropoietin
  • Peritoneal dialysis
    dependent / hemodialysis dependent patients who are receiving an
    erythropoietin
 

Dosage:

Adults:
Rubiject injection 5-10 ml (100-200 mg iron) 1-3 times / week depending on
the haemoglobin level.
Rubiject injection should be administered intravenously by slow injection
or infusion.

Children:
Under study conditions, there is limited data available. If there is
clinical requirement, Rubiject is recommended not to exceed 0.15 ml (3 mg
iron)/kg body weight 1-3 times/week depending on the haemoglobin level
also.

Recommended Adult Dosage(Chronic kidney disease patients):

Hemodialysis Dependent:
Undiluted Rubiject can be administered as 100 mg slow IV injection in 2-5
minutes or as an infusion of 100 mg, diluted in a maximum of 100 ml of 0.9%
NaCl in atleast 15 minutes per consecutive hemodialysis session for a total
dose of 1000 mg.

Non-Dialysis Dependent:
Rubiject is administered as a total dose of 1000 mg in 14 days as 200 mg
slow IV injection undiluted in 2-5 minutes on 5 different occasions within
14 days.

Peritoneal Dialysis Dependent:
Rubiject administered as a total dose of 1000 mg in 3 divided doses, given by slow IV infusion, within 28 days: 2 infusions of 300 mg in 1½ hours 14 days apart followed by one 400 mg infusion in 2½ hours 14 days later. The Rubiject dose should be diluted in a maximum of 250 ml of 0.9% NaCl. .

 

Presentations:

  • Inj 5′s