Product List

Generic:

Iron sucrose

Therapeutic Class:

Iron Plain

Composition:

Each 5 ml of Rubiject ampoule
contains:
Iron sucrose equivalent to elemental iron … 100 mg

Description:

Rubiject (iron sucrose
injection) is an aqueous complex of polynuclear iron (III)-hydroxide in
sucrose for intravenous use.

Indications:

Rubiject is recommended in:

• Conditions in which there
  is clinical requirement for rapid iron supply
• Active inflammatory bowel
  disease where oral iron preparations are ineffective
• Iron deficiency due to
  other reasons like final stages of pregnancy, non-responsiveness or
  non-compliance to oral iron therapy, malabsorption, before and after
  surgery etc.

Rubiject is also indicated in
the treatment of iron deficiency anaemia in chronic kidney disease patients
who are:

• Non-dialysis dependent
  patients receiving or not receiving an erythropoietin
• Peritoneal dialysis
  dependent / hemodialysis dependent patients who are receiving an
  erythropoietin

Dosage:

Adults:
Rubiject injection 5-10 ml (100-200 mg iron) 1-3 times / week depending on
the haemoglobin level.
Rubiject injection should be administered intravenously by slow injection
or infusion.

Children:
Under study conditions, there is limited data available. If there is
clinical requirement, Rubiject is recommended not to exceed 0.15 ml (3 mg
iron)/kg body weight 1-3 times/week depending on the haemoglobin level
also.

Recommended Adult Dosage(Chronic kidney disease patients):

Hemodialysis Dependent:
Undiluted Rubiject can be administered as 100 mg slow IV injection in 2-5
minutes or as an infusion of 100 mg, diluted in a maximum of 100 ml of 0.9%
NaCl in atleast 15 minutes per consecutive hemodialysis session for a total
dose of 1000 mg.

Non-Dialysis Dependent:
Rubiject is administered as a total dose of 1000 mg in 14 days as 200 mg
slow IV injection undiluted in 2-5 minutes on 5 different occasions within
14 days.

Peritoneal Dialysis Dependent:
Rubiject administered as a total dose of 1000 mg in 3 divided doses, given by slow IV infusion, within 28 days: 2 infusions of 300 mg in 1½ hours 14 days apart followed by one 400 mg infusion in 2½ hours 14 days later. The Rubiject dose should be diluted in a maximum of 250 ml of 0.9% NaCl. .

Presentations:

• Inj 5′s