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Generic:
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Glimepiride, Metformin HCl
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Therapeutic Class:
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Biguanide & S-Urea Combs
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Composition:
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Each Gluconormet (1 mg/ 500 mg)
contains glimepiride 1 mg and metformin hydrochloride 500 mg.
Each Gluconormet (2 mg/ 500 mg)
contains glimepiride 2 mg and metformin hydrochloride 500 mg.
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Description:
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| Gluconormet is an oral antidiabetic agent (glimepiride & metformin HCl) used in the management of type 2 diabetes.
Glimepiride:
Glimepiride (sulphonylurea class), mechanism of action appears to be
dependent on stimulating the release of insulin from functioning pancreatic
beta cells.
Metformin HCl:
Metformin improves glucose tolerance in patients with type 2 diabetes,
lowering both basal and postprandial plasma glucose.
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Indications:
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Gluconormet is indicated in the
treatment of patients with type 2 diabetes mellitus when diet, exercise and
single agent do not result in adequate glycemic control. |
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Dosage:
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| Gluconormet should be given once daily with full meal preferably in the evening. Therapy should be started with Gluconormet (glimepiride 1 mg & metformin 500 mg) one tablet daily. Depending upon the glycemic control, dose may be titrated to 2 tablets once daily.
Alternatively, the therapy may be started with Gluconormet (glimepiride 2 mg & metformin hydrochloride 500 mg) one tablet daily. Depending upon the glycemic control, dose may be titrated to 2 tablets once daily. The maximum daily dose of glimepiride is 8 mg and of metformin is 2000 mg. |
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Presentations:
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- Gluconormet (1 mg/500 mg) tablet is available in pack of 30’s.
- Gluconormet (2 mg/500 mg) tablet is available in pack of 30’s.
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