Products – Page 9 – AGP Pharma

Calfina INJ

Generic:

Tramadol HCl

Therapeutic Class:

Non-Narcotic Analgesics

Composition:

2 ml solution of Calfina
injection contains 100 mg of tramadol hydrochloride.

Description:

Calfina Injection contains Tramadol hydrochloride. Tramadol is a centrally acting synthetic opioid analgesic. The analgesic profile of tramadol is attributed to the binding of parent and M1 metabolite to μ-opioid receptors and weak inhibition of reuptake of norepinephrine and serotonin.

Indications:

Calfina Injection is indicated
for moderate to severe pain. Calfina injection is a potent medicinal
product for the relief of pain, e.g. in wound pain, fractures, severe nerve
pain, tumour pain, heart attack. It should not be used for minor pain.
The-effect sets in quickly and lasts for some hours.

Dosage:

The dose should be adjusted to
the intensity of the pain and the sensitivity of the individual patient.
The lowest effective dose for analgesia should generally be selected. The
total daily dose of 400 mg tramadol hydrochloride should not be exceeded,
except in special clinical circumstances.

The Calfina solution is for parenteral injection either intramuscularly, by slow intravenous injection or diluted in solution for administration by infusion or patient controlled analgesia.

Adults and children 12 years and over:
The usual dose of Calfina is 50 mg or 100 mg 4 to 6 hourly by either intramuscular or intravenous routes. Intravenous injections must be given slowly over 2–3 minutes. The dose should be adjusted according to the severity of the pain and the response.

For post-operative pain, an initial bolus of 100 mg is administered. During the 60 minutes following the initial bolus, further doses of 50 mg may be given every 10-20 minutes, up to a total dose of 250 mg including the initial bolus. Subsequent doses should be 50 mg or 100 mg 4-6 hourly up to a total daily dose of 400 mg.

Presentations:

Calfina® Injection 100 mg – Pack of 5 x 2 ml Ampoules

Calfina CR

Generic:

Tramadol HCl

Therapeutic Class:

Non-Narcotic Analgesics

Composition:

CALFINA CR tablets contain 100
mg of tramadol HCl in controlled-release formulation.

Description:

CALFINA CR (tramadol
hydrochloride) is a centrally acting synthetic analgesic in
controlled-release formulation.

Indications:

CALFINA CR is indicated for the
management of moderate to moderately severe chronic pain in adults who
require around-the-clock treatment of their pain for an extended period of
time.

Dosage:

Adults (18 years of age and over)

CALFINA CR should be initiated at a dose of 100 mg once daily and titrated
up as necessary by 100 mg increments every five days to relief of pain and
depending upon tolerability. CALFINA CR should not be administered at a
dose exceeding 300 mg per day.

Presentations:

Calfina CR is available in a
pack of 10 tablets.

Briax

Generic:

Piroxicam Beta-Cyclodextrin

Therapeutic Class:

ANTIRHEUMATIC NON-STEROID

Composition:

Each Briax tablet contains 20 mg
piroxicam (as Beta-Cyclodextrin) for oral administration.

Description:

Briax contains piroxicam which
is a member of the oxicam group of nonsteroidal anti-inflammatory drugs
(NSAIDs).

Indications:

Briax is indicated for the treatment of painful conditions and inflammation in rheumatic diseases (rheumatoid arthritis, osteoarthritis), musculoskeletal affections (tendinitis, bursitis, post-traumatic pain); post-operative pain & primary dysmenorrhea.

Dosage:

Adults

The recommended daily dose is one Briax tablet daily, preferably with or
after food.

Children

The use of Briax tablet in children is not recommended.

The Elderly

In elderly patients, it may be necessary to reduce the dosage (half a
tablet), and limit the duration of treatment. Again, it is preferable to
take the dose with or after food.

Presentations:

Briax tab 20 mg is available in blister pack of 20’s.

Axid Neo

Generic:

Esomeprazole Magnesium

Therapeutic Class:

Proton Pump Inhibitor

Composition:

Axid Neo 20 mg: Each Axid Neo capsule contains 20 mg of esomeprazole
Axid Neo 40 mg: Each Axid Neo capsule contains 40 mg of esomeprazole

Description:

Axid Neo is a proton pump
inhibitor that suppresses gastric acid secretion by specific inhibition of
the H+/K+-ATPase in the gastric parietal cell. By acting specifically on
the proton pump, Axid Neo blocks the final step in acid production, thus
reducing gastric acidity. This effect is dose-related up to a daily dose of
20 to 40 mg and leads to inhibition of gastric acid secretion.

Indications:

Treatment of Gastroesophageal Reflux Disease (GERD)
- Healing of Erosive Esophagitis
- Maintenance of Healing of Erosive Esophagitis
- Symptomatic Gastroesophageal Reflux Disease
Risk Reduction of NSAID-Associated Gastric Ulcer
H. pylori Eradication to Reduce the Risk of Duodenal Ulcer Recurrence
Pathological Hypersecretory Conditions Including Zollinger-Ellison Syndrome

Dosage:

Treatment of Gastroesophageal Reflux Disease (GERD)

Healing of Erosive Esophagitis

Axid Neo 20 mg or 40 mg once
daily for 4 to 8 weeks

Maintenance of Healing of Erosive Esophagitis

Axid Neo 20 mg once daily

Symptomatic Gastroesophageal Reflux Disease

Axid Neo 20 mg once daily for 4
to 8 weeks

Risk Reduction of
NSAID-Associated Gastric Ulcer

Axid Neo
20 mg or 40 mg once daily for up to 6 months

H. pylori Eradication to
Reduce the Risk of Duodenal Ulcer Recurrence

Triple Therapy (Axid Neo with amoxicillin and clarithromycin)

Axid Neo 40 mg once daily, in combination with amoxicillin 1000 mg twice daily and clarithromycin 500 mg twice daily for 10 days

Pathological Hypersecretory Conditions
Including Zollinger-Ellison Syndrome

Axid Neo 40 mg twice daily

Pediatric Use

1 to 11 years old (weight > 20 kg)

Healing of Erosive Esophagitis –
Axid Neo 20 mg once daily for 8 weeks

12 to 17 years old

Short-term treatment of GERD – Axid Neo 20 mg or 40 mg once daily
for 8 weeks

Presentations:

Axid Neo 20mg capsules 14’s
Axid Neo 40mg capsules 14’s

Analar

Generic:

Tizanidine

Therapeutic Class:

Muscle Relaxants, Central

Composition:

Each tablet contains 2 mg
tizanidine base.

Description:

Analar is a centrally acting α2-adrenergic agonist.

Indications:

Painful muscle spasms associated with static and functional disorders of the spine (cervical and lumber syndromes)
Painful muscle spasms following surgery e.g. for herniated intervertebral disc or osteoarthritis of the hip
Spasticity due to neurological disorders e.g. degenerative spinal cord diseases, chronic myelopathy, multiple sclerosis, cerebral palsy and cerebrovascular accidents.

Dosage:

Children:
The use of Analar in children is not recommended.Adults:
For relief of painful muscle spasms:The dose of Analar is 2 to 4 mg thrice daily. In severe conditions, an extra dose of 2 or 4 mg may be taken at night.For spasticity due to neurological disorders:
The initial daily dose may be increased stepwise at half-weekly or weekly intervals by 2 to 4 mg but initially it should not exceed 6 mg given in 3 divided doses. The optimum therapeutic response is achieved when daily dose is between 12 and 24 mg, administered in 3 to 4 divided doses. The total daily dose should not exceed 36 mg.

Presentations:

Analar 2 mg tablet is availble in pack of 10’s

Anafortan Plus

Generic:

Phloroglucinol, Trimethylphloroglucinol

Therapeutic Class:

Antispasmodic and Anticholinergic Plain

Composition:

Each Anafortan Plus coated tablet contains:

Hydrated Phloroglucinol- – – – – — – – – – – – – — – – – 80 mg
Corresponding to anhydrous phloroglucinol- – – — 62.233 mg
Trimethylphloroglucinol- – – – – – —- – – – – – – – – — 80 mg

Each Anafortan Plus injection 4ml contains:

Hydrated Phloroglucinol– – – – – – – -. – – – – – – – – – 40 mg
Trimethylphloroglucinol- – – – – – – – – – – – – – – – – – – 0.04 mg

Description:

An antispasmodic which acts on the smooth muscles in the gastrointestinal & urogenital pathways and relieves pain associated with spasm.

Indications:

Spasm associated with irritable bowel syndrome (IBS)
Spasm associated with diarrhoea and dysentery
Renal colic
Biliary colic
Dysmenorrhoea
Delayed labour

Dosage

Tab: 1 tablet 3 times daily; maximum 6 tablets daily
Inj: 1-3 ampoules IM or IV daily

Presentations:

Tabs 30s
Inj 6’s

All-D Drops

Generic:

Cholecalciferol (Vitamin D3)

Therapeutic Class:

Vitamin D3

Composition:

Each All-D drop contains Cholecalciferol (vitamin D3) – 400 IU.

Description:

All-D (Cholecalciferol) is one
of the five forms of vitamin D. Cholecalciferol is synthesized in the skin
from 7-dehydrocholesterol under the action of ultraviolet B (UVB) radiation
from sunlight depending on the intensity of the UVB in the sunlight –
determined by latitude, season, cloud cover, and altitude – and the age and
degree of pigmentation of the skin. Vitamin D is important for the
absorption of calcium and for the functioning of calcium in the body.

Indications:

All-D (Cholecalciferol) is used to treat or prevent many conditions caused by lack of vitamin D, especially conditions of the skin or bones. Vitamin D is used to treat and prevent bone disorders (such as rickets & Osteomalacia), prevent bone loss (osteoporosis). Vitamin D drops (or other supplements) are given to breast-fed infants because breast milk usually has low levels of vitamin D.

Dosage:

Infants & Children below 4 years: 1 drop daily.

Children above 4 years: 2 drops daily.

Adults: 2-3 drops daily or as directed by the physician.

Presentations:

All-D drops – 10 ml

Algocin

Generic:

Ciprofloxacin

Therapeutic Class:

Fluoroquinolones

Composition:

Each Algocin tablet contains (USP) equivalent to Ciprofloxacin 250 mg and 500 mg tablets.

Description:

Algocin is a synthetic broad
spectrum antibacterial agent for oral administration. It has invitro
activity against a wide range of gram-positive and gram-negative organisms.

Indications:

Urinary tract infections
Chronic bacterial prostatitis
Lower respiratory tract infections
Acute sinusitis
Skin and skin structure infections
Bone & joint infections
Complicated intra-abdominal infections (used in combination with metronidazole)
Infectious diarrhea
Typhoid & para typhoid
Uncomplicated cervical and urethral gonorrhea
Acute uncomplicated
cystitis in females
Inhalational anthrax (post-exposure)

Dosage:

Location of infections	Severity	Unit Dose	Frequency	Usual Durations
Urinary Tract	Acute uncomplicated	250 mg	q 12 h	3 days
	Mild/moderate	250 mg	q 12 h	7 to 14 days
	Severe/complicated	500 mg	q 12 h	7 to 14 days
Chronic Bacterial Prostatitis	Mild/moderate	500 mg	q 12 h	28 days
Lower Respiratory Tract	Mild/moderate	500 mg	q 12 h	7 to 14 days
Lower Respiratory Tract	Severe/complicated	750 mg	q 12 h	7 to 14 days
Acute Sinusitis	Mild/moderate	500 mg	q 12 h	10 days
Skin and Skin Structure	Mild/moderate	500 mg	q 12 h	7 to 14 days
Skin and Skin Structure	Severe/complicated	750 mg	q 12 h	7 to 14 days
Bone and Joint	Mild/moderate	500 mg	q 12 h	4 to 6 weeks
Bone and Joint	Severe/complicated	750 mg	q 12 h	4 to 6 weeks
Intra-Abdominal*	Complicated	500 mg	q 12 h	7 to 14 days
Infectious Diarrhea	Mild/moderate/severe	500 mg	q 12 h	5 to 7 days
Typhoid Fever	Mild/moderate	500 mg	q 12 h	10 days
Urethral and Cervical Gonococcal Infections	Uncomplicated	250 mg	single dose	Single dose
Inhalational anthrax (post-exposure)		500 mg	q 12 h	60 days

* used in conjunction with
metronidazole

Presentations:

Algocin 250 mg tablet is available in pack of 10’s
Algocin 500 mg tablet is available in pack of 10’s

Abnil

Generic:

Orlistat

Therapeutic Class:

Antiobesity

Composition:

Each Abnil capsule contains 120
mg orlistat.

Description:

Abnil (Orlistat) is a lipase
inhibitor for obesity management.

Indications:

Abnil is indicated:

For obesity management including weight loss and weight maintenance when used in conjunction with a reduced-calorie diet.
To reduce the risk for weight regain after prior weight loss.
For obese patients with an initial body mass index in the presence of other risk factors (eg, hypertension, diabetes, dyslipidemia).

Dosage:

The recommended dose of Abnil is
one capsule three times daily with each main meal containing fat (during or
up to 1 hour after the meal).

Presentation:

Abnil 120 mg capsule is available in the pack of 30’s.