Products – Page 5 – AGP Pharma

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Toni-5

Generic:

Phosphoric acid, Lysine , Monohydrate, Dimethyl amino ethanol, Sorbitol, Calcium , gluconoglucoheptonate

Therapeutic Class:

TONICS

Composition:

Each 5 ml contains

Lysine monohydrochloride (PFM Specs.) ………………… 200 mg
Calcium gluconoglucoheptonate (Ph. Eur.)………………..150 mg
Dimethyl-amino-ethanol (pyro) glutamate (PFM Specs.)…. 50 mg
Phosphoric acid (Ph. Eur.)………………………………… 0.025 ml
Sorbitol……………………………………………………. 750 mg

Description:

Toni-5 syrup combines various factors to stimulate growth in young children.Dimethylaminoethanol (pyro) glutamate, which acts on interneuronal transmissions.Lysine. calcium and phosphorus, which promote growth of muscles & bone tissues in length & weight

Indications:

Fatigue of any nature (growth disorders, anorexia, malnutrition)
Asthenia
Decreased Alertness
Convalescence
General Weakness

Dosage:

Usual dosage: 1 teaspoonful/ 5 kg body weight daily in 2-3 divided doses.

The following daily dosages should be divided 2-3 times or as directed by the physician.

For neonates: 1 teaspoonful/ 5 kg body weight.

Before 6 months of age: 1 teaspoonful .

From 6 to 12 months of age: 2 teaspoonfuls.

From 12 months to 6 years of age: 3 teaspoonfuls.

Above 6 years of age: 4 to 6 teaspoonfuls.

Presentations:

120 ml syrup

Spasler P

Generic:

Hyoscine Butyl Bromide

Therapeutic Class:

Antispasmodic and Anticholinergic Plain

Composition:

Each 5 ml of Spasler-P syrup contains

hyoscine butyl bromide (B.P.) 5 mg

Description:

Spasler P syrup has a selective
antispasmodic effect on the smooth muscles of the gastrointestinal, biliary
and urogenital tracts. It has the great advantage that despite its
antispasmodic effect it is virtually devoid of the side effects usually
associated with atropine like drugs

Indications:

For the short term treatment of

Colics due to renal and
biliary calculi
Acute pain due to spasm of
bile duct, urinary passage or gastro-intestinal tract
Pancreatitis
Pains of uncertain genesis
in the abdominal region
Postoperative pain
Spastic conditions of the
female genital system

Dosage:

Infant: 1 teaspoon 3 times daily

1- 6 years: 1-2 teaspoons 3 times daily

Over 6 years: 2 teaspoons 3-5 times daily

Presentations:

5 mg/5 ml syrup 60 ml

Spasler Neo

Generic:

Mebeverine HCl

Therapeutic Class:

Antispasmodic and Anticholinergic Plain

Composition:

Each Spasler Neo tablet contains

mebeverine hydrochloride B.P 135 mg

Description:

Spasler Neo is myotropic
antispasmodic, which acts through specific action on smooth muscles of
gastrointestinal tract. It does not affect autonomic nervous system,
therefore its use is not associated with usual anticholinergic side
effects. For this reason Spasler Neo can be prescribed in patients
suffering from BPH or glaucoma

Indications:

Irritable bowel syndrome
associated with diarrhoea or constipation
Alternating constipation
with diarrhoea
Abdominal distension
GI spasm associated with
organic diseases like diverticulitis, regional enteritis, duodenal
ulcer and dysentery
Biliary dyskinesia

Dosage:

The usual recommended dosage of
Spasler Neo is one tablet of 135 mg three times daily. The tablet should
preferably be taken 20 minutes before meals

Presentations:

135 mg tab 30’s

Sinaxamol

Generic:

Orphenadrine Citrate, Paracetamol

Therapeutic Class:

Muscle relaxants central

Composition:

Each film-coated tablet of
Sinaxamol contains:

Orphenadrine Citrate B. P…….35 mg
Paracetamol B.P……450 mg

Description:

Sinaxamol tablet contains
orphenadrine citrate and paracetamol, the combined muscle relaxant action
of orphenadrine citrate and the analgesic effect of paracetamol provides
in-depth relief from pain associated with skeletal muscle spasm. Orphenadrine
Citrate is an centrally effective muscle relaxant. It is readily absorbed
from the gastro-intestinal tract and is almost completely metabolized.
Paracetamol possess analgesic and antipyretic actions.

Indications:

Any condition involving skeletal
muscle spasm secondary to

Acute trauma
Herniated disc
Fibrositis characterized by low back pain
Muscular strains and pain
Sciatica
Stiff neck
Muscular rheumatism
Muscular spasm found in frozen shoulder
Arthritis
Bursitis
Sprains
Acute torticollis
Contusions
Acute traumatic lumbar strain
Osteoarthritis
Dysmenorrhoea

Dosage:

Adults: Two tablets of Sinaxamol three times daily

Children: Not recommended

Presentations:

Sinaxamol tab 100’s

Sinaxamol Extra

Generic:

Paracetamol, Orphenadrine
Citrate

Therapeutic Class:

Muscle relaxants central

Composition:

Each tablet of Sinaxamol Extra
contains:

Orphenadrine Citrate B. P………..50 mg
Paracetamol B.P……………650 mg

Description:

Sinaxamol Extra contains
orphenadrine citrate and paracetamol, the combined muscle relaxant action
of orphenadrine citrate and the analgesic effect of paracetamol provides
in-depth relief from pain associated with skeletal muscle spasm.
Orphenadrine Citrate is an centrally effective muscle relaxant. It is
readily absorbed from the gastro-intestinal tract and is almost completely
metabolized. Paracetamol possess analgesic and antipyretic actions.

Indications:

Any condition involving skeletal
muscle spasm secondary to

Acute trauma
Herniated disc
Fibrositis characterized by
low back pain
Muscular strains and pain
Sciatica
Stiff neck
Muscular rheumatism
Muscular spasm found in
frozen shoulder
Arthritis
Bursitis
Sprains
Acute torticollis
Contusions
Acute traumatic lumbar
strain
Osteoarthritis
Dysmenorrhoea

Dosage:

Adults: One tablet of Sinaxamol Extra twice daily.

Children: Not recommended

Presentations:

Sinaxamol Extra tab 30’s

Rubiject Injection

Generic:

Iron sucrose

Therapeutic Class:

Iron Plain

Composition:

Each 5 ml of Rubiject ampoule
contains:
Iron sucrose equivalent to elemental iron … 100 mg

Description:

Rubiject (iron sucrose
injection) is an aqueous complex of polynuclear iron (III)-hydroxide in
sucrose for intravenous use.

Indications:

Rubiject is recommended in:

Conditions in which there
is clinical requirement for rapid iron supply
Active inflammatory bowel
disease where oral iron preparations are ineffective
Iron deficiency due to
other reasons like final stages of pregnancy, non-responsiveness or
non-compliance to oral iron therapy, malabsorption, before and after
surgery etc.

Rubiject is also indicated in
the treatment of iron deficiency anaemia in chronic kidney disease patients
who are:

Non-dialysis dependent
patients receiving or not receiving an erythropoietin
Peritoneal dialysis
dependent / hemodialysis dependent patients who are receiving an
erythropoietin

Dosage:

Adults:
Rubiject injection 5-10 ml (100-200 mg iron) 1-3 times / week depending on
the haemoglobin level.
Rubiject injection should be administered intravenously by slow injection
or infusion.

Children:
Under study conditions, there is limited data available. If there is
clinical requirement, Rubiject is recommended not to exceed 0.15 ml (3 mg
iron)/kg body weight 1-3 times/week depending on the haemoglobin level
also.

Recommended Adult Dosage(Chronic kidney disease patients):

Hemodialysis Dependent:
Undiluted Rubiject can be administered as 100 mg slow IV injection in 2-5
minutes or as an infusion of 100 mg, diluted in a maximum of 100 ml of 0.9%
NaCl in atleast 15 minutes per consecutive hemodialysis session for a total
dose of 1000 mg.

Non-Dialysis Dependent:
Rubiject is administered as a total dose of 1000 mg in 14 days as 200 mg
slow IV injection undiluted in 2-5 minutes on 5 different occasions within
14 days.

Peritoneal Dialysis Dependent:
Rubiject administered as a total dose of 1000 mg in 3 divided doses, given by slow IV infusion, within 28 days: 2 infusions of 300 mg in 1½ hours 14 days apart followed by one 400 mg infusion in 2½ hours 14 days later. The Rubiject dose should be diluted in a maximum of 250 ml of 0.9% NaCl. .

Presentations:

Inj 5′s

Rigix

Generic:

Cetirizine Dihydrochloride

Therapeutic Class:

Antihistamines Systemic

Composition:

Each Rigix tablet contains cetirizine dihydrochloride 10 mg.
Each ml of Rigix oral solution contains 1 mg of cetirizine dihydrochloride

Description:

Cetirizine, an active metabolite
of hydroxyzine, is an antihistamine; its principal effects are mediated via
selective inhibition of peripheral H1 receptors and are indicated in
allergic conditions

Indications:

Seasonal allergic rhinitis
Perennial allergic rhinitis
Chronic idiopathic urticaria

Dosage:

Tablets:
Adults & children above 12 years: One 10 mg tablet dailyRigix oral solution can be taken without regard to food consumption.

Children 6 months to <2 years for Perennial Allergic Rhinitis and Chronic Urticaria:

The recommended dose of Rigix oral solution in children 6 months to 23 months of age is 2.5 mg (½ teaspoonful) once daily. The dose in children 12 to 23 months of age can be increased to a maximum dose of 5 mg per day, given as ½ teaspoonful (2.5 mg) every 12 hours.

Children 2 to 5 years for Chronic Urticaria:

The recommended initial dose of Rigix oral solution in children aged 2 to 5 years is 2.5 mg (½ teaspoonful) once daily. The dosage in this age group can be increased to a maximum dose of 5 mg per day given as 1 teaspoonful (5 mg) once daily, or as ½ teaspoonful (2.5 mg) given every 12 hours.

Children 6 years & above:

2 teaspoonfuls once daily or 1 teaspoonful twice daily.

Presentations:

10 mg tabs 30’s,
Oral sol 120ml,

Protege

Generic:

Lactobacillus acidophilus,
Lactobacillus rhamnosus, Bifidobacterium lactis, Bifidobacterium bifidum,
Galactooligosaccharide

Therapeutic Class:

Antidiarrheal Microorganisms

Composition:

Each 2 g Sachet of Protégé is a blend of 4 different strains with 10 billion COLONY FORMING UNITS of human gut flora like friendly bacteria include:

Lactobacillus acidophilus
Lactobacillus rhamnosus
Bifidobacterium lactis
Bifidobacterium bifidum
A PREBIOTIC Galactooligosaccharide (GOS)
Lactobacillus acidophilus

Description:

Protégé is Probiotic preparation. Probiotics are live microorganisms which when administered in adequate amounts, they confer a health benefit on the host. Popular probiotic strains include the Lactobacillus spp., Bifidobacterium spp. and coccus spp.

Indications:

Acute & Chronic Infectious Diarrhea
Traveler’s Diarrhea
Antibiotic associated Diarrhea
Inflammatory Bowel Disease (IBS)
Lactose Intolerance

Dosage:

Children & Adult: Take 1‐2
sachets per time, dissolving into water with temperature not more than 40℃.

Presentations:

2 g Sachet 10’s,

Pozemet

Generic:

Metformin HCl, Pioglitazone HCl

Therapeutic Class:

Glitazone& Biguanide Combinations

Composition:

Pozemet Tab 15 mg/500 mg:

Each tablet contains 15 mg pioglitazone hydrochloride with 500
mg metformin hydrochloride.

Pozemet Tab 15 mg/850 mg:

Each tablet contains 15 mg pioglitazone hydrochloride with 850
mg metformin hydrochloride.

Description:

Pozemet tablet contains
two oral antihyperglycemic drugs, pioglitazone hydrochloride and metformin
hydrochloride. They are used in the management of type 2 diabetes.

Pioglitazone
hydrochloride acts primarily by decreasing insulin resistance. It improves
sensitivity to insulin in muscle and adipose tissue and inhibits hepatic
gluconeogenesis. It reduces circulating insulin levels and improves
glycemic control.

Metformin hydrochloride
improves glucose tolerance by lowering both basal and postprandial plasma
glucose. It improves insulin sensitivity by increasing peripheral glucose
uptake and utilization. It also decreases hepatic glucose production and
intestinal absorption of glucose.

Indications:

Pozemet is indicated as an adjunct to diet and exercise to
improve glycemic control in type 2 diabetic patients who are already
treated with a combination of pioglitazone and metformin or whose diabetes
is not adequately controlled with metformin alone or for those patients who
have initially responded to pioglitazone alone and require additional
glycemic control.

Dosage:

Starting dose of Pozemet should be based on the patient’s current treatment
of pioglitazone and/or metformin. Pozemet should be given with meals in
divided daily doses to reduce the gastrointestinal side effects associated
with metformin.

Starting Dose:

For patients inadequately controlled on metformin monotherapy:

Pozemet may be
initiated at either 15 mg/500 mg or 15 mg/850 mg tablet strength based on
usual starting dose of pioglitazone (15-30 mg daily), once or twice daily
and gradually titrated after assessing adequacy of therapeutic response.

For patients who initially responded to pioglitazone monotherapy & require additional glycemic control:

Pozemet may be
initiated at either 15 mg/500 mg twice daily or 15 mg/850 mg tablet
strength once daily based on the usual starting doses of metformin (500 mg
twice daily or 850 mg daily) and gradually titrated after assessing
adequacy of therapeutic response.

For patients switching from combination therapy of pioglitazone plus metformin as separate tablets:

Pozemet may be
initiated with either 15 mg/500 mg or 15 mg/850 mg tablet strengths based
on the dose of pioglitazone and metformin already being taken.

Maximum Recommended Dose:

The maximum recommended dose for pioglitazone is 45 mg & metformin is 2,550 mg daily in adults.

Presentations:

Pozemet 15 mg/500 mg is available in 14’s
Pozemet 15 mg/850 mg is available in 14’s

Poze

Generic:

Pioglitazone HCl

Therapeutic Class:

GLITAZONE A-DIABS PLAIN

Composition:

Poze tablet 15 mg:
Each Poze tablet contains pioglitazone hydrochloride equivalent to can also be used in combina pioglitazone … 15 mg

Poze tablet 30 mg:
Each Poze tablet contains pioglitazone hydrochloride equivalent to pioglitazone … 30 mg

Poze tablet 45 mg:
Each Poze tablet contains pioglitazone hydrochloride equivalent to pioglitazone … 45 mg

Description:

Poze (pioglitazone
hydrochloride) is an oral antidiabetic agent that is used in the management
of type 2 diabetes. It acts primarily by decreasing insulin resistance. It
improves sensitivity to insulin in muscle and adipose tissue and inhibits
hepatic gluconeogenesis. It reduces circulating insulin levels and improves
glycemic control.

Indications:

Poze is indicated for type 2 diabetes mellitus (non-insulin dependant diabetes mellitus) as an adjunct to diet control and exercise.

Poze is recommended for monotherapy. It can also be used in combination with sulfonylureas, metformin or insulin when diet and exercise plus the single antidiabetic agent do not result in glycemic control.

Dosage:

Poze tablets can be taken once daily with or without meals. Skipping meals, while taking Poze is not advisable since this can lead to hypoglycemia.

Monotherapy:
Poze monotherapy is initiated at 15 mg or 30 mg once daily for those patients whose diabetes is not controlled with diet and exercise.
Dose can be increased up to 45 mg once daily for those patients who do not adequately respond to initial dose of Poze.

Combination therapy:
Combined therapy should be considered for those patients who do not adequately respond to monotherapy with Poze.

Sulfonylureas:
Poze can be initiated with sulfonylureas at 15 mg to 30 mg once daily. If the patient experiences hypoglycemia, dose of sulfonylureas should be adjusted (decreased).

Metformin:
Poze can be initiated with metformin at 15 mg to 30 mg once daily. The therapeutic effects of Poze are seen in combination with metformin in patients regardless of dose (low or high) of metformin which the patients are receiving.

Insulin:
Poze can be initiated with insulin at 15 mg to 30 mg once daily. While giving Poze in combination with insulin, dose of insulin can be decreased by 10% to 25% if the patient is hypoglycemic or if plasma glucose concentrations decrease to less than 100 mg/dl. Further adjustments should be done based on glucose-lowering response. If there is a particular risk of hypoglycemia, patients on insulin should be given 15 mg of Poze once daily initially.

Maximum recommended dose:
The maximum dose of Poze should not exceed 45 mg once daily.

Presentations:

Poze 15 mg is available in 14’s
Poze 30 mg is available in 14’s
Poze 45 mg is available in 14’s